Company Filing History:
Years Active: 1998-2001
Title: The Innovations of Guang-Ping Gao
Introduction
Guang-Ping Gao is a prominent inventor based in Havertown, PA (US). He has made significant contributions to the field of gene therapy, particularly through his work with adenoviruses. With a total of 5 patents, Gao's innovations are paving the way for advancements in the treatment of genetic disorders.
Latest Patents
Gao's latest patents include a novel adenovirus gene therapy vehicle and cell line. This invention provides a packaging cell line that expresses adenovirus E1/E4, allowing for the generation of recombinant adenoviruses that are deleted in both gene regions. The E1/E4 deleted recombinant adenovirus is capable of expressing a selected transgene product in cells, both in vivo and in vitro. This recombinant virus holds promise for treating genetic disorders. Another significant patent involves recombinant adenovirus and adeno-associated virus, cell lines, and methods of production and use. This patent details a method for enhancing the efficiency of transduction of a recombinant AAV into a target cell, which involves infecting the target cell with a recombinant AAV that comprises a selected transgene under the control of regulatory sequences.
Career Highlights
Gao is affiliated with the University of Pennsylvania, where he continues to conduct research and develop innovative solutions in gene therapy. His work has garnered attention for its potential impact on medical treatments and therapies.
Collaborations
Some of his notable coworkers include James M. Wilson and Krishna J. Fisher, who have collaborated with Gao on various projects related to gene therapy and adenoviral research.
Conclusion
Guang-Ping Gao's contributions to the field of gene therapy through his innovative patents are significant. His work continues to inspire advancements in the treatment of genetic disorders, showcasing the importance of research and collaboration in the scientific community.