Company Filing History:
Years Active: 1999-2002
Title: Innovations by Gregory T. Mulhern
Introduction
Gregory T. Mulhern is a notable inventor based in Branford, Connecticut. He has made significant contributions to the field of biopolymer analysis and separation technologies. With a total of three patents to his name, Mulhern's work has advanced the capabilities of electrophoretic analysis.
Latest Patents
One of his latest patents is an "Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments." This invention features an integrated instrument designed for high-capacity electrophoretic analysis of biopolymer samples. It includes a specialized high-voltage electrophoretic module that allows for the concurrent separation of 80 or more samples. The device incorporates a thermal control module with Peltier heat transfer devices to manage temperature and gradients in the electrophoretic medium. Detection is achieved through a transmission imaging spectrograph that spatially focuses and spectrally resolves the detection region of all migration lanes. The spectrograph utilizes a transmission dispersion element and a CCD array for signal detection, with advanced signal analysis techniques to enhance results.
Another significant patent by Mulhern is related to "Separation of charged particles by a spatially and temporally varying electric field." This invention provides a method and device for separating charged particles based on their diffusivities in a separation medium. It is particularly effective for sizing and separating DNA fragments, generating DNA fragment length polymorphism patterns, and sequencing DNA. The method employs a spatially periodic electric potential that cycles between on and off states, allowing for efficient separation of charged particles. The device is microfabricated, enabling rapid separation in multiple lanes.
Career Highlights
Gregory T. Mulhern has been instrumental in advancing biopolymer analysis technologies through his innovative patents. His work at Curagen Corporation has positioned him as a key figure in the field of biotechnology. His inventions have not only contributed to scientific research but have also paved the way for practical applications in genetic analysis.
Collaborations
Mulhern has collaborated with notable figures in the industry, including Jonathan Marc Rothberg and Gregory T. Went. These partnerships have further enhanced the impact of his inventions and contributed to advancements in biopolymer research.
Conclusion
Gregory T. Mulhern's contributions to the field of biopolymer analysis through his innovative patents have significantly advanced the capabilities of electroph