Location History:
- Shenandoah, VA (US) (1992 - 1993)
- Lansdale, PA (US) (2002)
Company Filing History:
Years Active: 1992-2002
Title: Gregory L Tewalt: Innovator in Pharmaceutical Chemistry
Introduction
Gregory L Tewalt is a notable inventor based in Shenandoah, VA (US). He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of processes that aid in the synthesis of important compounds.
Latest Patents
Tewalt holds 3 patents, with his latest innovations focusing on the preparation of acetonides and biosynthetic production of specific acids. His process for preparing acetonides involves a one-step reaction of a carboxylic acid halide, a 1,2-aminoalcohol, and 2-alkoxypropene or 2,2-dialkoxypropane in an ether solvent, along with an inorganic base. Additionally, he has developed a two-step reaction scheme that produces acetonides, which can serve as intermediates in the production of HIV protease inhibitors. His work on biosynthetic production includes the enzymatic hydrolysis of lovastatin acid, yielding compounds that are useful as anti-hypercholesterolemic agents.
Career Highlights
Gregory L Tewalt is currently associated with Merck & Company, Inc., where he continues to innovate in the pharmaceutical sector. His research has led to advancements that are crucial for developing treatments for various health conditions.
Collaborations
Tewalt has collaborated with notable coworkers, including Rebecca L Dabora and Steven J Cianciosi, contributing to a dynamic research environment that fosters innovation.
Conclusion
Gregory L Tewalt's work exemplifies the impact of innovative thinking in pharmaceutical chemistry. His patents and ongoing research play a vital role in the development of new therapeutic agents.