Location History:
- Austin, TX (US) (2010 - 2011)
- Nederland, TX (US) (2014)
Company Filing History:
1 out of 7 
2 out of 832,680 Years Active: 2010-2014
Title: Gregory F. Lopreato: Innovator in Aptamer Technology
Introduction
Gregory F. Lopreato is a notable inventor based in Austin, TX, who has made significant contributions to the field of aptamer technology. With a total of three patents to his name, he has developed innovative methods for identifying and detecting target molecules through the use of aptamers.
Latest Patents
One of his latest patents is titled "Lariat aptamer: aptamer candidate exclusion by nuclease digestion." This method involves identifying aptamers that bind to target molecules by contacting an oligonucleotide library with a target molecule and digesting unbound oligonucleotides with various nucleases. The unbound oligonucleotides are susceptible to digestion due to their complementary flanking sequences, which form predictable secondary structures known as Lariat Aptamers. The bound aptamers are protected from digestion and become enriched, allowing for further selection and amplification under stringent conditions. This method can be utilized in conjunction with other aptamer selection techniques, such as SELEX.
Another significant patent focuses on "Systems and methods for detecting target analytes." This method includes contacting a target substance with a substrate that has a first receptor bound to it. The target substance binds to this receptor, and a second biotinylated receptor associated with the target substance is introduced. An anti-biotin antibody conjugated to a paramagnetic particle is then contacted with the substrate, facilitating the detection of the target substance.
Career Highlights
Throughout his career, Gregory has worked with various companies, including Fabrico Technology Inc. His work has been instrumental in advancing the understanding and application of aptamer technology in various fields.
Collaborations
Gregory has collaborated with notable individuals in his field, including Robert C. Chin, enhancing the impact of his innovative work.
Conclusion
Gregory F. Lopreato's contributions to aptamer technology through his patents and collaborations highlight his role as a significant inventor in this specialized area. His innovative methods for identifying and detecting target molecules continue to influence research and applications in the field.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.