Gregory Ellis

Title: Gregory Ellis - Innovator in Cellular Uptake Enhancement

Introduction

Gregory Ellis is a notable inventor based in Madison, WI (US). He has made significant contributions to the field of molecular delivery systems, particularly focusing on enhancing cellular uptake of cargo molecules. His innovative approach utilizes boronation techniques to improve the efficiency of molecular transport into cells.

Latest Patents

Gregory Ellis holds a patent titled "Boronate-mediated delivery of molecules into cells." This invention outlines methods for enhancing cellular uptake of cargo molecules by boronating the cargo molecule, specifically with one or more phenylboronic acid groups. The patent details how cellular uptake includes at least partial uptake into the cytosol. The boronation process involves ligating, crosslinking, or otherwise bonding phenylboronic acids that contain a reactive group to a cargo molecule. Additionally, the invention encompasses certain phenylboronates that serve as boronation reagents, boronated oligopeptides, and kits designed to enhance cellular uptake through boronation.

Career Highlights

Gregory Ellis is associated with the Wisconsin Alumni Research Foundation, where he continues to develop and refine his innovative ideas. His work has garnered attention for its potential applications in various fields, including drug delivery and therapeutic interventions.

Collaborations

Throughout his career, Gregory has collaborated with esteemed colleagues such as Ronald Thaddeus Raines and Michael Palte. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Gregory Ellis stands out as an influential inventor in the realm of molecular delivery systems. His innovative patent on boronate-mediated delivery showcases his commitment to enhancing cellular uptake of cargo molecules. His contributions have the potential to impact various scientific and medical fields significantly.