Company Filing History:
1 out of 22 
1 out of 3 
1 out of 8 Years Active: 1993-1997
Title: Innovations in Biotechnology: The Contributions of Gregory C. Holtz
Introduction
Gregory C. Holtz is an accomplished inventor based in San Diego, California, who has made significant strides in the field of biotechnology. With a total of three patents to his name, his contributions have advanced the understanding and production of important biological compounds.
Latest Patents
Among his noteworthy patents, the latest involves the production of insulin-like growth factor-1 (IGF-1) in methylotrophic yeast cells. This innovative method allows for the preparation of IGF-1, a naturally occurring polypeptide, by utilizing methylotrophic yeast transformants that contain DNA encoding IGF-1 alongside essential signal sequences. The process is meticulously designed to promote the secretion of proteins from yeast host cells, utilizing a specific promoter region derived from methanol-responsive genes in methylotrophic yeast. This patent also details novel DNA constructs and recombinant yeast strains that serve critical roles in the expression and secretion of IGF-1.
Career Highlights
Gregory C. Holtz has notably worked with organizations such as the Salk Institute Biotechnology Industrial Associates, Inc. and the Salk Institute Biotechnology/Industrial Associates, Inc. His work in these esteemed institutions has placed him at the forefront of biotechnological research and innovation.
Collaborations
Throughout his career, Holtz has collaborated with esteemed colleagues, including Russell A. Brierley and Geneva R. Davis. These partnerships have contributed to the successful development of pioneering techniques and methods in the biotechnology realm.
Conclusion
Gregory C. Holtz's work exemplifies the spirit of innovation in biotechnology. His advancements in the production of key biological compounds through novel methods highlight the importance of collaboration and research in driving forward scientific understanding and applications. As he continues to contribute to the field, his legacy of innovation will undoubtedly leave a lasting impact.