Gregorio Del Val

Title: Innovations by Gregorio Del Val in Allergy Treatment

Introduction

Gregorio Del Val is an accomplished inventor based in San Diego, California. He has made significant contributions to the field of allergy treatment through his innovative research and patents. With a total of seven patents to his name, Del Val's work focuses on reducing allergenic potential in various proteins.

Latest Patents

One of Del Val's latest patents addresses the alleviation of the allergenic potential of airborne and contact allergens by utilizing thioredoxin. Thioredoxin is a small dithiol protein that acts as a specific reductant for allergenic proteins, particularly those found in pollen and animal and plant sources. The targeted proteins contain disulfide bonds that are reduced to the sulfhydryl level by thioredoxin. This reduction process renders the proteins less allergenic and more digestible. Skin tests conducted with sensitized dogs demonstrated that treating pollens with reduced thioredoxin prior to injection significantly decreased their allergenicity. Additionally, studies indicated that pollen proteins reduced by thioredoxin serve as effective immunotherapeutic agents for mitigating allergic reactions.

Another notable patent by Del Val focuses on increasing the digestibility of food proteins through thioredoxin reduction. Similar to his work with allergens, thioredoxin reduces disulfide bonds in major food proteins, making them less allergenic and more digestible. Skin tests and feeding experiments with sensitized dogs showed that food treated with reduced thioredoxin prior to ingestion resulted in decreased allergenicity. Furthermore, studies revealed enhanced digestion of food proteins by digestive enzymes following thioredoxin reduction.

Career Highlights

Gregorio Del Val is affiliated with the University of California, where he conducts his research and develops his innovative solutions. His work has garnered attention for its potential to improve the quality of life for individuals suffering from allergies.

Collaborations

Del Val collaborates with notable colleagues, including Bob B Buchanan and Rosa M Lozano, who contribute to his research efforts and innovations.

Conclusion

Gregorio Del Val's innovative work in allergy treatment through the use of thioredoxin has the potential to revolutionize how allergic reactions are managed. His contributions to the field are significant and continue to pave the way for future advancements in allergy research and treatment.