Company Filing History:
2 out of 11 
2 out of 11 Years Active: 2004-2007
Title: Innovations of Graham McCreath
Introduction
Graham McCreath is a notable inventor based in Edinburgh, GB. He has made significant contributions to the field of biotechnology, particularly in the purification of proteins. With a total of four patents to his name, McCreath's work has advanced the understanding and application of protein purification techniques.
Latest Patents
One of McCreath's latest patents involves the purification of fibrinogen from fluids by precipitation and hydrophobic chromatography. This invention provides a method for the partial purification of fibrinogen from milk, which includes transferring the protease enzyme present in the milk into the whey phase while removing or partitioning fibrinogen into another phase. Additionally, he has developed a method for obtaining fibrinogen from a fluid by contacting it with a hydrophobic interaction chromatography resin, allowing the fibrinogen to bind to the resin and be subsequently eluted. Another significant patent focuses on fusion proteins incorporating lysozyme. This process involves expressing a fusion protein in the milk of a transgenic, non-human, placental mammal, which links the peptide to be expressed with lysozyme. The fusion protein can be separated from the milk and cleaved to yield the target peptide.
Career Highlights
Throughout his career, Graham McCreath has worked with several prominent companies, including PPL Therapeutics (Scotland) Limited and Pharming Intellectual Property B.V. His innovative approaches have contributed to advancements in the biotechnology sector, particularly in protein engineering and purification.
Collaborations
McCreath has collaborated with notable individuals in his field, including Ian Robert Cottingham and Udell Michael. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Graham McCreath's contributions to biotechnology through his patents and collaborations highlight his role as a significant inventor in the field. His work continues to influence advancements in protein purification and biotechnology applications.