This inventor holds 4 USPTO granted patents and 1 EPO patent. Top assignee: St. Jude Children's Research Hospital. Active years: 1999-2008.
Location History:
- Memphis, TN (US) (1999 - 2002)
- Carmel, IN (US) (2008)
Company Filing History:
Years Active: 1999-2008
Title: Innovations of Gotz Von Bulow
Introduction
Gotz Von Bulow is a notable inventor based in Carmel, IN (US). He has made significant contributions to the field of immunology, particularly through his work on lymphocyte surface receptors. With a total of 4 patents, his innovations have the potential to impact therapeutic approaches in various autoimmune conditions.
Latest Patents
One of his latest patents describes a lymphocyte surface receptor that binds CAML and methods of use thereof. This novel lymphocyte receptor protein, along with its DNA sequence, plays a crucial role in the calcium activation pathway. The protein, or genetically engineered constructs encoding it, has been shown to enhance lymphocyte response and identify ligands of the protein receptor. Antibodies generated from this invention can be utilized for diagnostic therapeutics. The protein and DNA can also serve diagnostic purposes and help identify agents that modulate the calcium-induced activation pathway. A significant advantage of this invention is its ability to activate receptors found on all B cells while selectively targeting a subset of T cells. This specificity is particularly beneficial when regulating B cell responses, especially during infections or to mitigate complications from autoimmune conditions such as rheumatoid arthritis and glomerulonephritis.
Career Highlights
Gotz Von Bulow is affiliated with St. Jude Children's Research Hospital, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in improving immune responses and therapeutic strategies.
Collaborations
He collaborates with Richard J Bram, contributing to the advancement of research in immunology and related fields.
Conclusion
Gotz Von Bulow's innovative work in the field of lymphocyte receptors showcases his commitment to advancing medical science. His patents hold promise for enhancing therapeutic approaches to autoimmune diseases and improving patient outcomes.