Company Filing History:
Years Active: 1994-1996
Title: Gordon J MacDonald: Innovator in Glycoprotein Hormones
Introduction
Gordon J MacDonald is a notable inventor based in Piscataway, NJ (US). He has made significant contributions to the field of glycoprotein hormones, holding a total of 2 patents. His work focuses on enhancing the understanding and application of biologically active ligands.
Latest Patents
One of his latest patents is titled "Analogs of glycoprotein hormones having altered receptor binding." This invention pertains to an alpha, beta-heterodimeric polypeptide that exhibits binding affinity to vertebrate luteinizing hormone (LH) receptors and vertebrate follicle stimulating hormone (FSH) receptors. The polypeptide comprises a glycoprotein hormone alpha-subunit and a non-naturally occurring beta-subunit, which is a chain of amino acids with specific subsequences derived from various hormones.
Another significant patent is related to a "Sensitive bioassay using monoclonal antibodies which bind to." This invention provides a quantitative assay for determining the amount of biologically active ligands, such as human chorionic gonadotropin and luteinizing hormone, present in a sample. The assay involves contacting the sample with the receptor and a monoclonal antibody, allowing for the formation of a complex that can be quantitatively analyzed. Additionally, this invention includes kits for quantitatively assaying biologically active ligands or their receptors.
Career Highlights
Gordon J MacDonald has worked at prestigious institutions, including the University of Medicine and Dentistry of New Jersey and Columbia University. His career reflects a commitment to advancing scientific knowledge and practical applications in the field of biochemistry.
Collaborations
Throughout his career, he has collaborated with notable individuals such as William R Moyle and Robert K Campbell. These collaborations have contributed to the development of innovative solutions in his area of expertise.
Conclusion
Gordon J MacDonald is a distinguished inventor whose work in glycoprotein hormones has led to valuable patents and advancements in the field. His contributions continue to influence research and applications in biochemistry.
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