Company Filing History:
7 out of 1,217 
1 out of 12 
1 out of 254 
Years Active: 1978-1984
Title: Glen R Gale: Innovator in Antitumor Pharmaceutical Compounds
Introduction
Glen R Gale is a notable inventor based in Charleston, SC, who has made significant contributions to the field of pharmaceuticals, particularly in the development of antitumor compounds. With a total of nine patents to his name, his work has garnered attention for its innovative approaches to cancer treatment.
Latest Patents
Gale's groundbreaking work includes his latest patent for a compound known as N-Phosphonacetyl-L-aspartato (1,2-diaminocyclohexane)platinum(II). This compound has illustrated promising antitumor activity against various cancers, including murine leukemia L1210, B-16 tumors, Colon 38 tumors, and Ehrlich ascites tumor. Research indicates its efficacy across dosages of 5-60 mg/kg of body weight, particularly when combined with cyclophosphamide (CY) and hydroxyurea (HU). Moreover, Gale's compound can be paired in a treatment strategy with cisplatin at an optimal ratio of about 10:1, achieving significantly improved therapeutic outcomes compared to parent compounds.
Career Highlights
Glen R Gale has collaborated with esteemed institutions such as the United States of America as represented by the Department of Health. His innovative contributions have positioned him as a key figure in advancing pharmaceutical technologies aimed at combating cancer.
Collaborations
Throughout his career, Gale has worked alongside reputable professionals in the field, including Paul Schwartz and Sandra J Meischen. Their collective expertise has further enriched the research and development processes behind Gale's notable inventions.
Conclusion
Glen R Gale stands out as an influential inventor whose dedication to developing effective cancer treatments has the potential to impact countless lives. His innovative patents and collaborations exemplify the crucial role inventors play in the advancement of medical science and patient care.