Giulia Casorati

Title: Giulia Casorati: Innovator in Tumor-Specific T Cell Production

Introduction

Giulia Casorati is a prominent inventor based in Milan, Italy. She has made significant contributions to the field of immunology, particularly in the development of innovative methods for producing tumor-specific T cells. With a total of 2 patents, her work is paving the way for advancements in cancer treatment.

Latest Patents

One of her latest patents is titled "TCR and uses thereof." This invention relates to a TCR or functional variant that has antigenic specificity for CD1c molecules associated with a self-lipid, preferably mLPA or a derivative thereof. The patent also covers relative polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions. Importantly, it discusses the uses of this TCR and related products, particularly in the treatment and prevention of hematological disorders.

Another significant patent is "Method for the production of activated marked tumor-specific T cells and use thereof in treatment of tumors." This method involves co-cultivating tumor cells from a patient with T cells from the same patient. The process includes incubating tumor cells with fusion proteins, inhibiting tumor cell proliferation, and co-cultivating until T cell activation is achieved. This method is noted for its efficiency and simplicity.

Career Highlights

Giulia has worked with notable organizations such as Science Park Raf S.p.a. and Ospedale San Raffaele S.r.l. Her experience in these institutions has contributed to her expertise in the field of immunology and cancer research.

Collaborations

Throughout her career, Giulia has collaborated with esteemed colleagues, including Paolo Dellabona and Claudia De Lalla. These collaborations have further enriched her research and innovations in tumor immunology.

Conclusion

Giulia Casorati's contributions to the field of immunology, particularly in the production of tumor-specific T cells, highlight her role as an influential inventor. Her patents and collaborations reflect her commitment to advancing cancer treatment methodologies.