Company Filing History:
8 out of 90 
6 out of 26 
5 out of 4,179 
Years Active: 1982-2007
Title: Innovations and Contributions of Giovanni Pastrone in Cardiac Surgery
Introduction: Giovanni Pastrone, based in Los Gatos, California, is a remarkable inventor with a significant portfolio of 30 patents. His groundbreaking inventions primarily focus on advancements in cardiac surgery, particularly involving the aorta and related medical devices.
Latest Patents: Among his latest patents are two notable innovations: an aortic occluder with an associated filter and methods of use during cardiac surgery, and a balloon arterial cannula designed for filtering blood. These devices incorporate a mesh for filtering blood flow within arteries, such as the aorta. Key features include a structure designed to open and close the mesh, a mechanism for actuation, and a balloon occluder formed from a flexible material. The methodologies outlined in these patents involve the introduction of the mesh into a blood vessel to capture embolic materials, adjustments to the mesh during filtration, and the inflation of the balloon occluder to temporarily occlude the vessel. This is followed by the deflation of the balloon occluder and removal of the mesh and any captured foreign matter. Visualization techniques are also integrated to ensure effective filtration. Additionally, Pastrone's patent for aortic atherectomy describes a method for removing plaque from the aorta, incorporating a filter deployed downstream of a mobile plaque, and utilizing an atherectomy assembly to excise the plaque while capturing emboli for safe removal.
Career Highlights: Giovanni Pastrone has made significant strides in medical technology and innovation through his work with companies such as Embolx, Inc. and Oximetrix, Inc. His contributions have greatly enhanced the efficacy and safety of cardiac surgical procedures.
Collaborations: Throughout his career, Pastrone has collaborated with talented professionals in the field, including Denise R. Barbut and Jonathan D. Root. These partnerships have fostered innovative solutions and continued progress in cardiac surgical techniques.
Conclusion: Giovanni Pastrone's dedication to innovation and advancement in cardiac surgery is reflected in his extensive patent portfolio and valuable contributions to medical technology. His work continues to have a lasting impact on the field, improving patient outcomes and redefining the standards of care in cardiac surgery.