Location History:
- Pisa, IT (1986)
- Coltano, IT (1987)
Company Filing History:
Years Active: 1986-1987
Title: Innovations of Giorgio Staibano in Diphosphonic Acids
Introduction
Giorgio Staibano is a notable inventor based in Pisa, Italy. He has made significant contributions to the field of chemistry, particularly in the preparation of diphosphonic acids. With a total of two patents to his name, Staibano's work has implications in pharmacology and materials science.
Latest Patents
Staibano's latest patents include a process for the preparation of diphosphonic acids. This invention outlines a method that starts from carboxylic acids, a phosphorus trihalide, and orthophosphorous acid, all without the use of solvents. The process employs specific molar ratios and conditions to maintain a fluid reaction mixture, allowing hydrolysis to occur solely with boiling water. Another significant patent involves pharmacologically active biphosphonates. These biphosphonic acids, characterized by a general formula, exhibit valuable properties in treating urolithiasis and as inhibitors of bone reabsorption. Notably, the compound 4-amino-1-hydroxybutan-1,1-biphosphonic acid is reported to be between 100 and 300 times more active than Cl.sub.2 MDP.
Career Highlights
Giorgio Staibano is associated with Istituto Gentili S.p.a., where he continues to innovate in his field. His work has garnered attention for its practical applications in medicine and chemistry.
Collaborations
Staibano collaborates with Sergio Rosini, contributing to advancements in their shared field of expertise.
Conclusion
Giorgio Staibano's contributions to the preparation of diphosphonic acids highlight his innovative spirit and dedication to advancing chemical processes. His patents reflect significant advancements that could impact various medical treatments.