This inventor holds 6 USPTO granted patents and 4 published patent applications and 2 EPO patents. Top assignee: Applied Biosystems, LLC. Active years: 2011-2019.
Location History:
- Essex, MA (US) (2011 - 2013)
- Carlsbad, CA (US) (2012 - 2019)
Company Filing History:
Years Active: 2011-2019
Title: Innovations of Inventor Gina Costa
Introduction
Gina Costa is a prominent inventor based in Carlsbad, California. She has made significant contributions to the field of biotechnology, particularly in the area of nucleic acid sequencing. With a total of six patents to her name, her work has advanced the methods used in genetic analysis.
Latest Patents
One of her latest patents is titled "Reagents, methods, and libraries for bead-based sequencing." This invention provides methods for determining a nucleic acid sequence by performing successive cycles of duplex extension along a single-stranded template. The cycles include steps of extension, ligation, and cleavage. In certain embodiments, the methods utilize extension probes containing phosphorothiolate linkages and employ agents suitable for cleaving such linkages. The invention also outlines methods for determining information about a sequence using at least two distinguishably labeled probe families. In some cases, the methods acquire less than 2 bits of information from each of a plurality of nucleotides in the template during each cycle. Additionally, the sequencing reactions can be performed on templates attached to immobilized beads. The invention further includes sets of labeled extension probes containing phosphorothiolate linkages and allows for multiple sequencing reactions on a single template by removing initializing oligonucleotides and extended strands.
Career Highlights
Gina has worked with notable companies in the biotechnology sector, including Applied Biosystems, LLC and Ab Advanced Genetic Analysis Corporation. Her experience in these organizations has contributed to her expertise in genetic sequencing technologies.
Collaborations
Throughout her career, Gina has collaborated with esteemed colleagues such as Lev Kotler and Kevin J McKernan. These partnerships have fostered innovation and development in her field.
Conclusion
Gina Costa's contributions to biotechnology, particularly in nucleic acid sequencing, have made her a significant figure in the industry. Her innovative patents and collaborations reflect her dedication to advancing genetic analysis technologies.