Gilda H Loew

Title: Gilda H. Loew: Innovator in Analgesic Development

Introduction

Gilda H. Loew is a prominent inventor based in Atherton, California. She has made significant contributions to the field of analgesics, focusing on nonaddicting alternatives to traditional pain relief methods. With a total of 3 patents, her work has paved the way for innovative approaches to pain management.

Latest Patents

Loew's latest patents include groundbreaking developments in orally active nonaddicting analgesics. She describes stereoisomerically pure forms of normorphine analogs that exhibit superior analgesic and nonaddicting qualities. Additionally, her work introduces a method for separating diastereomeric forms of N-sec-alkyl-substituted analogs using hydrocarbyl diesters of normorphine derivatives. Furthermore, she discloses a new method for preparing N-methylalkylmethyl derivatives of normorphine and norcodeine, employing corresponding methyl alkyl ketones and a reducing agent. Her novel N-sec-alkyl derivatives of norcodeine and normorphine, which contain four or five carbon atoms in the sec-alkyl group, demonstrate strong agonist potency combined with strong antagonist qualities, indicating low addiction potential.

Career Highlights

Throughout her career, Gilda H. Loew has worked with esteemed organizations such as SRI International and Leland Stanford Junior University. Her research has significantly impacted the development of safer analgesic options, contributing to advancements in medical science.

Collaborations

Loew has collaborated with notable colleagues, including John A. Lawson and Joseph I. DeGraw. These partnerships have further enriched her research and innovation in the field of analgesics.

Conclusion

Gilda H. Loew's contributions to the development of nonaddicting analgesics highlight her role as a leading inventor in the medical field. Her innovative approaches and collaborations continue to influence pain management strategies.