Gidon Pilarski

Title: Gidon Pilarski: Innovator in Pharmaceutical Chemistry

Introduction

Gidon Pilarski is a notable inventor based in Holon, Israel. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the production of fluoxetine, a well-known antidepressant.

Latest Patents

Gidon Pilarski holds a patent for the "Production of fluoxetine and new intermediates." This patent details a method for preparing 4-methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenyl propylamine by reacting 3-dimethylamino-1-phenyl-1-propanol with haloformate. The process involves obtaining a substituted propyl carbamate, which is then hydrolyzed under basic conditions to yield methylamino-1-phenyl-1-propanol. This compound is subsequently converted to fluoxetine through a reaction with 4-halobenzotrifluoride. The method also results in certain substituted carbamates as intermediates.

Career Highlights

Gidon Pilarski is associated with Teva Pharmaceutical Industries Limited, a leading global pharmaceutical company. His work at Teva has focused on innovative approaches to drug development and production.

Collaborations

Gidon has collaborated with notable colleagues such as Eduard Schwartz and Joseph Kaspi, contributing to advancements in pharmaceutical research and development.

Conclusion

Gidon Pilarski's work in the production of fluoxetine showcases his expertise and innovation in pharmaceutical chemistry. His contributions continue to impact the field positively.