Company Filing History:
3 out of 4 
2 out of 35 
1 out of 13 Years Active: 1979-1993
Title: Gianfranco Fedeli: Innovator in Polydeoxyribonucleotide Research
Introduction
Gianfranco Fedeli is a notable inventor based in Milan, Italy. He has made significant contributions to the field of biochemistry, particularly in the area of polydeoxyribonucleotides. With a total of 9 patents to his name, Fedeli's work has advanced the understanding and application of nucleic acids in various scientific domains.
Latest Patents
Among his latest patents, Fedeli has developed processes for obtaining chemically defined and reproducible polydeoxyribonucleotides. One of his notable inventions involves the depolymerization of stabilized solutions of highly polymerized and nicked polydeoxyribonucleotides. This process is achieved through the stabilizing aggregation of raw nucleic acids, followed by controlled heating and the removal of hydrogen bonds in double-stranded filaments. The result is a polydeoxyribonucleotide known as Defibrotide, which has a specific formula of random sequence.
Career Highlights
Throughout his career, Gianfranco Fedeli has worked with several prominent companies in the pharmaceutical and biotechnological sectors. Notable among these are Hepar Chimie S.a. and Crinos Industria Farmacobiologica S.p.a. His innovative approaches have contributed to advancements in drug development and therapeutic applications.
Collaborations
Fedeli has collaborated with esteemed colleagues in his field, including Fernando Fussi and Giuseppe Diamantini. These partnerships have fostered a collaborative environment that has led to significant breakthroughs in his research.
Conclusion
Gianfranco Fedeli's contributions to the field of polydeoxyribonucleotide research exemplify the impact of innovation in biochemistry. His patents and collaborations continue to influence the scientific community and pave the way for future advancements.