Company Filing History:
Years Active: 2012-2013
Title: Giacomo Mancini: Innovator in Medical Diagnostics
Introduction
Giacomo Mancini is a notable inventor based in Millstone, NJ (US). He has made significant contributions to the field of medical diagnostics, particularly in understanding inflammatory bowel diseases. With a total of 2 patents, his work has the potential to impact patient care and treatment options.
Latest Patents
Mancini's latest patents focus on splice variants of the human IL-23 receptor (IL-23R) mRNA. His research includes the cloning and identification of these splice variants caused by alternative splicing of the IL-23R mRNA in humans. A total of twenty-five different IL-23R transcripts have been identified, including a novel exon deletion isoform, denoted as Δ9. This isoform is predominantly present in colon and cervical tissues, and a decrease in its levels is observed in inflamed colon tissues of Crohn's patients. His work also describes a quantitative assay to measure different IL-23R isoforms, providing a method for predicting Crohn's disease by measuring the Δ9 isoform of IL-23R.
Career Highlights
Mancini is currently associated with Medical Diagnostic Laboratories, LLC, where he continues to advance his research in medical diagnostics. His innovative work has positioned him as a key figure in the field, contributing to the understanding of complex diseases.
Collaborations
Some of his notable coworkers include Raymond Yu and Shih-hsin Kan, who have collaborated with him on various projects related to his patents.
Conclusion
Giacomo Mancini's contributions to medical diagnostics through his innovative patents highlight the importance of research in understanding and predicting inflammatory bowel diseases. His work continues to pave the way for advancements in patient care and treatment methodologies.