Gert Bolt

Title: Gert Bolt: Innovator in Coagulation Factor Research

Introduction

Gert Bolt is a notable inventor based in Vaerloese, Denmark. He has made significant contributions to the field of biotechnology, particularly in the development of coagulation factors. With a total of six patents to his name, Bolt's work has advanced the understanding and production of essential proteins in medical applications.

Latest Patents

Among his latest patents is a method for the production of a Factor VIII polypeptide. This invention involves culturing a mammalian cell that expresses the Factor VIII polypeptide under specific conditions. The method includes using a cell culture medium that comprises a C2-domain ligand and isolating the expressed Factor VIII polypeptide from the mammalian cell by suitable means. Another significant patent is related to modified coagulation factors, specifically conjugated Factor VIII molecules fused to a polypeptide, such as an antibody binding protein or an Fc domain. These innovations are crucial for improving therapeutic options for patients with bleeding disorders.

Career Highlights

Gert Bolt has worked with prominent companies in the biotechnology sector, including Novo Nordisk A/S and Novo Nordisk Healthcare AG. His experience in these organizations has allowed him to contribute to groundbreaking research and development in the field of coagulation factors.

Collaborations

Throughout his career, Bolt has collaborated with esteemed colleagues, including Thomas Dock Steenstrup and Lars Thim. These partnerships have fostered a collaborative environment that has led to significant advancements in their shared field of research.

Conclusion

Gert Bolt's contributions to the field of biotechnology, particularly in the area of coagulation factors, have been invaluable. His innovative patents and collaborations with leading companies and researchers highlight his commitment to advancing medical science.