Gerhard Z Urcher

Title: Gerhard Z Urcher: Innovator in Catechol Derivatives

Introduction

Gerhard Z Urcher is a notable inventor based in Basel, Switzerland. He has made significant contributions to the field of pharmacology through his innovative work on catechol derivatives. His research focuses on compounds that possess valuable pharmacological properties, particularly in the inhibition of the enzyme catechol-O-methyltransferase (COMT).

Latest Patents

Gerhard Z Urcher holds a patent for catechol derivatives, specifically those described by the formula ##STR1##. These derivatives include ester and ether forms that are hydrolyzable under physiological conditions. The compounds are designed to inhibit COMT, a magnesium-dependent enzyme that plays a crucial role in the methylation of catechol substrates. This inhibition is particularly relevant for extraneuronal catecholamines and therapeutically active substances with a catechol structure. His patent represents a significant advancement in the development of pharmacological agents.

Career Highlights

Throughout his career, Gerhard Z Urcher has been associated with Hoffmann-La Roche Inc., a leading company in the pharmaceutical industry. His work has contributed to the understanding and application of catechol derivatives in medical treatments.

Collaborations

Gerhard has collaborated with esteemed colleagues such as Karl Bernauer and Janos Borgulya. Their combined expertise has furthered research in the field of pharmacology and the development of innovative compounds.

Conclusion

Gerhard Z Urcher's contributions to the field of pharmacology through his patent on catechol derivatives highlight his role as an influential inventor. His work continues to impact the development of therapeutic agents that can enhance medical treatments.