Company Filing History:
Years Active: 1990-1993
Title: Innovations and Contributions of Gerald T Nepom
Introduction
Gerald T Nepom is a notable inventor based in Bainbridge Island, WA (US). He has made significant contributions to the field of medical diagnostics, particularly in relation to diabetes and rheumatoid arthritis. With a total of 2 patents, his work has had a meaningful impact on understanding genetic predispositions to these conditions.
Latest Patents
Gerald's latest patents include methods for identifying the DQw3.2 allele associated with an increased risk of diabetes. These methods utilize the discovery of the DQw3.2 variant, which identifies a specific allelic polymorphism at a single gene locus. One preferred method employs a labeled probe to detect the DQw3.2 allele, estimating the size of the hybridizable DNA fragment generated by a specific restriction endonuclease to determine the presence of the allele. Another method involves serologic detection of the DQw3.2 allele, where immunocomplexes formed between two different monoclonal antibodies and separate portions of a cell collection are detected to ascertain the presence or absence of the allele. Additionally, he holds a patent for a diagnostic probe for rheumatoid arthritis predisposition, which includes oligonucleotide probes capable of specifically hybridizing with relevant genetic markers.
Career Highlights
Throughout his career, Gerald has worked with esteemed organizations such as Virginia Mason Research Center and Genetic Systems Corporation. His experience in these institutions has allowed him to advance his research and contribute to significant medical advancements.
Collaborations
Gerald has collaborated with various professionals in his field, including his coworker Barbara S Nepom. Their joint efforts have furthered research in genetic predispositions to diseases.
Conclusion
Gerald T Nepom's innovative work in the field of medical diagnostics has led to important advancements in understanding genetic risks associated with diabetes and rheumatoid arthritis. His contributions continue to influence research and diagnostics in these critical areas.