Gerald Krystal

Title: Gerald Krystal: Innovator in SHIP Polypeptide Modulation

Introduction

Gerald Krystal is a prominent inventor based in Vancouver, Canada. He has made significant contributions to the field of biotechnology, particularly in the modulation of SHIP polypeptides. With a total of nine patents to his name, Krystal's work has the potential to impact therapeutic approaches in various medical conditions.

Latest Patents

Among his latest patents, one notable invention is the "Methods for identifying allosteric modulators of SHIP polypeptides." This invention provides a method for identifying allosteric modulators of a SHIP polypeptide, wherein said SHIP polypeptide is contacted with a test compound, and wherein said SHIP polypeptide comprises an allosteric site selected from the group consisting of a SHIP C2 domain and a SHIP PH domain. Another significant patent is titled "SHIP 1 modulators," which includes the use of pelorol, related compounds, and pharmaceutical compositions thereof as modulators of SHIP 1 activity. This invention also provides novel terpene compounds capable of modulating SHIP 1 activity and methods of synthesis thereof.

Career Highlights

Throughout his career, Krystal has worked with various organizations, including Cv Molecular Therapeutics, Inc. His innovative research has positioned him as a key figure in the biotechnology sector, particularly in the development of therapeutic agents targeting SHIP polypeptides.

Collaborations

Krystal has collaborated with notable professionals in his field, including Simon W. Rabkin and Alice Mui. These collaborations have further enhanced his research and contributed to the advancement of his inventions.

Conclusion

Gerald Krystal's contributions to the field of biotechnology, particularly in the modulation of SHIP polypeptides, highlight his innovative spirit and dedication to advancing medical science. His patents and collaborations reflect a commitment to improving therapeutic options for various health conditions.