Location History:
- Bridgewater, NJ (US) (1990 - 2000)
- Flemington, NJ (US) (2000 - 2001)
Company Filing History:
Years Active: 1990-2001
Title: Innovations of George W. Matcham: Pioneering Chiral Compounds
Introduction
George W. Matcham, an innovative inventor based in Bridgewater, NJ, has made significant contributions to the field of chemistry, particularly in the development of chiral compounds and fungicidal compositions. With a remarkable portfolio of 11 patents, Matcham's work emphasizes the importance of stereochemistry in developing effective agricultural solutions.
Latest Patents
Among his latest patents, Matcham has developed compositions for chiral imidazole fungicides. These compositions offer methods for inhibiting the growth of various fungi, including those that are phytotoxic to plants. By utilizing a single isomer, his approach allows for selective inhibition of fungal growth while minimizing harmful effects on plant health.
Another noteworthy patent involves the enzymatic synthesis of chiral amines, specifically using 2-amino propane as the amine donor. This process highlights his innovative approach to stereoselective synthesis, where he efficiently converts ketones into chiral amines using transaminase enzymes. For example, his method allows for the production of (S)-1-methoxy-2-aminopropane from methoxyacetone, demonstrating the potential for practical applications in pharmaceuticals and agriculture.
Career Highlights
Matcham's career is marked by his tenure at notable organizations such as Celgene Corporation and Celgro. His work within these companies has contributed to advancements in biochemical and agricultural technology, underscoring his expertise in the field.
Collaborations
Throughout his career, Matcham has collaborated with key figures in the industry, including David I. Stirling and Andrew L. Zeitlin. These collaborations have helped to foster innovative ideas and drive the research necessary for developing new compounds and methodologies.
Conclusion
George W. Matcham's inventive spirit and dedication to advancing chiral chemistry have led to significant breakthroughs in fungicide development and amine synthesis. With a strong foundation of patents and impactful collaborations, he continues to play a pivotal role in enhancing agricultural practices and exploring new avenues within scientific research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.