George W Katsilometes

Title: George W Katsilometes: Innovator in Chemiluminescent Assays

Introduction

George W Katsilometes is a notable inventor based in Davis, CA (US). He has made significant contributions to the field of immunoassays and chemiluminescence, holding a total of 3 patents. His work has advanced the understanding and application of vitamin B12 assays and novel signal solutions.

Latest Patents

One of his latest patents focuses on a Vitamin B12 assay, which utilizes immunoassays for vitamin B12 using novel monoclonal antibodies. These antibodies target the intrinsic factor:vitamin B12 complex and the vitamin B12 binding site on intrinsic factor. Another significant patent involves the use of nonmetallic tetrapyrrole molecules, which catalyze the production of light through chemiluminescence. This occurs in the presence of a signal solution at a pH ranging from about 10.0 to about 14.0, along with appropriate oxidants and luminescent reactants. The addition of various components, such as electron transport facilitators and surfactants, enhances the output of light. These tetrapyrrole molecules can be used alone or attached to haptens or macromolecules, serving as labels in the preparation of chemiluminescent assays.

Career Highlights

Throughout his career, George W Katsilometes has worked with several companies, including Monitor Diagnostics, Inc. and Tritech Partners. His expertise in the field has allowed him to contribute to various innovative projects and advancements in assay technology.

Collaborations

He has collaborated with notable professionals, including Mohammad T Pourfarzaneh, further enhancing the impact of his work in the scientific community.

Conclusion

George W Katsilometes is a distinguished inventor whose work in chemiluminescent assays and vitamin B12 immunoassays has made a lasting impact on the field. His innovative patents and collaborations continue to influence advancements in assay technology.