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George S Sach

This inventor holds 32 USPTO granted patents, primarily in Histamine Antagonists. Top assignee: Smith Kline & French Laboratories Limited. Active years: 1976-1990.

USPTO Granted Patents = 32

% Patents Active = 100.0

Average Co-Inventor Count = 1.7

ph-index = 6

Forward Citations = 99(Granted Patents)

Location History:

Welwyn, EN (1976 - 1978)
Welwyn, GB (1979 - 1990)

Company Filing History:

32 out of 362

Smith Kline & French Laboratories Limited

patents

Years Active: 1976-1990

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Areas of Expertise:

Histamine H.sub.1 Antagonists

Histamine H.sub.2 Antagonists

Pyridine Derivatives

Pharmacologically Active

Alkoxypyridyl Compounds

Pyrimidone Derivatives

Cyclobutenediones

Aminoalkyl Compounds

Thiadiazole-1-Oxides

Pyridyl-2-Oxy

Alkoxy-Pyridine

Nitro-Pyridines

32 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 4894372 - Pyridine compounds which have useful histamine-H.sub.2 antagonist (1990-01-16),

2. 4863936 - 3,5-Substituted-2-pyridyl-alkylaminocyclobutenediones having histamine (1989-09-05),

3. 4771058 - 3,4-diamino-1,2,5-thiadiazole-1-oxides having histamine H.sub.1 (1988-09-13),

4. 4758576 - Pyridine derivatives and use as histamine H.sub.2 antagonists (1988-07-19),

5. 4727076 - Tetrahydroquinolinylalkyl amino pyridones and ring homologues thereof, (1988-02-23),

6. 4665078 - 2-(3-amino-5-halo-2-pyridylalkylamino)-pyrimidones useful as histamine (1987-05-12),

7. 4640926 - 3,5-Substituted-2-pyridylalkylaminothiadiazoles having histamine H.sub.1 (1987-02-03),

8. 4607107 - (4-aminoalkyl-2-pyridyl alkyl)guanidines (1986-08-19),

9. 4584381 - 5-(Nitro or halogen)-3-(alkyl)-2-(aminoalkyl)pyridines (1986-04-22),

10. 4574126 - Pyridine derivatives histamine H.sub.2 -antagonists (1986-03-04),

11. 4551466 - Pyridyl-2-oxy-propyl-1H-1,2,4-triazole-3,5-diamines (1985-11-05),

12. 4537891 - 2-(3,5-Substituted-2-pyridylalkylamino)-5-benzyl-4-pyrimidones (1985-08-27),

13. 4537890 - 2-(3,5-Substituted-2-pyridylalkylamino)-5-oxopyridylmethyl-4-pyrimidones (1985-08-27),

14. 4535163 - 2-Aminoalkyl-pyridine derivatives (1985-08-13),

15. 4532252 - 3,5-Substituted-2-pyridylalkylamino compounds having histamine H.sub.1 (1985-07-30),

Title: Innovator in Pharmacology - George S. Sach

Introduction

George S. Sach is a prominent inventor based in Welwyn, GB. With an impressive portfolio of 32 patents, he has made significant contributions to the field of pharmacology, particularly in the development of histamine antagonists.

Latest Patents

Among his latest patents, Sach has developed pyridine compounds that serve as useful histamine H₂ antagonists. This invention involves 2-pyridine derivatives that are substituted in the 4-position with a dialkylamino, piperidinyl, or pyrrolidinylalkyl group, showcasing important histamine H₂-antagonist activity. Additionally, he has worked on 3,5-substituted-2-pyridyl-alkylaminocyclobutenediones, which consist of various substituted aminoalkylamino-2-pyridine derivatives, proving to be effective as histamine H₁ antagonists.

Career Highlights

George S. Sach's career has been defined by his innovative work at Smith Kline & French Laboratories Limited, where he has played a vital role in advancing pharmaceutical research. His inventions have had a positive impact on the treatment of allergies and related conditions by targeting histamine receptors.

Collaborations

Throughout his career, Sach has collaborated with notable scientists, including Graham J. Durant and Charon R. Ganellin. These partnerships have enriched his research and contributed to the development of his groundbreaking patents.

Conclusion

George S. Sach stands out as a significant figure in the pharmaceutical industry, with a strong focus on creating innovative solutions for histamine-related challenges. His work continues to inspire future generations of inventors and researchers in the field of pharmacology.

Profile summary based on public USPTO records.

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