George S N Hui

Title: Innovations by George S N Hui

Introduction

George S N Hui is a notable inventor based in Honolulu, HI (US). He has made significant contributions to the field of immunology, particularly in the development of malaria vaccines. With a total of 2 patents, his work showcases the potential of innovative approaches to combat infectious diseases.

Latest Patents

Hui's latest patents include a malaria immunogenic composition and a baculovirus-produced Plasmodium falciparum vaccine. The malaria immunogenic composition utilizes the silkworm/baculovirus system to produce recombinant Major Merozoite Surface Protein 1 (MSP1). This method is advantageous due to its low cost and high yield. The recombinant virus, BmNPV-Sp42, was used to infect silkworms, resulting in the expression of MSP1 (Sp42). The Sp42 protein was recognized by specific antibodies, indicating its potential as an antigen for malaria vaccines. His second patent involves compositions comprising a polypeptide expressed from insect cells harboring a baculovirus vector, which is designed to induce the production of anti-p42 antibodies.

Career Highlights

Hui has worked at the University of Hawai'i, where he has contributed to research and development in the field of vaccine technology. His innovative work has positioned him as a key figure in the fight against malaria.

Collaborations

Some of his notable coworkers include Lap-Yin Pang and Walter K K Ho, who have collaborated with him on various research projects.

Conclusion

George S N Hui's contributions to malaria vaccine development highlight the importance of innovative research in addressing global health challenges. His work exemplifies the potential of using alternative expression systems for vaccine production.