George S Lewis

Title: The Innovations of George S. Lewis

Introduction

George S. Lewis is an accomplished inventor based in Durham, NC (US). He has made significant contributions to the field of biochemistry, particularly in the development of cationic lipids. His work focuses on creating new compounds that facilitate the transfer of nucleic acids and peptides into cells, which has important implications for gene therapy and drug delivery.

Latest Patents

George S. Lewis holds a patent for his invention related to cationic lipids. The patent describes new cationic lipids and intermediates in their synthesis that are useful for transfecting nucleic acids or peptides into prokaryotic or eukaryotic cells. The lipids consist of one or two substituted arginine, lysine, or ornithine residues, or derivatives thereof, linked to a lipophilic moiety. These lipids form complexes when mixed with polyanions such as nucleic acids or peptides, allowing for efficient transfer into cells without significant toxicity.

Career Highlights

George S. Lewis is currently employed at Gilead Sciences, Inc., where he continues to innovate in the field of biochemistry. His work has contributed to advancements in therapeutic techniques that leverage the properties of cationic lipids for medical applications.

Collaborations

Throughout his career, George has collaborated with notable colleagues, including Randolph B. DePrince and Kevin L. Facchine. These collaborations have fostered a productive environment for research and development in their shared field of expertise.

Conclusion

George S. Lewis is a prominent inventor whose work on cationic lipids has the potential to revolutionize the way nucleic acids and peptides are delivered into cells. His contributions to biochemistry are significant and continue to impact the field positively.