Company Filing History:
Years Active: 1976-1979
Title: George Peter Peruzzotti: Innovator in Prostaglandin Analogues
Introduction
George Peter Peruzzotti is a notable inventor based in Middleton, WI (US). He has made significant contributions to the field of medicinal chemistry, particularly in the development of prostaglandin analogues. With a total of 5 patents to his name, Peruzzotti's work has implications for cardiovascular health.
Latest Patents
Among his latest patents are the "Cycloalkenyl analogues of prostaglandin A" and "Cycloalkenyl analogues of prostaglandin F." These analogues involve modifications to the natural prostaglandins, where the C.sub.13 -C.sub.20 chain is replaced by a cycloalkenyl or hydroxycycloalkenyl moiety. This innovative approach retains the natural sequential positions of the vinylene radical and hydroxyl group, which has been shown to inhibit platelet aggregation in vitro and exhibit useful cardiovascular activity in vivo.
Career Highlights
George Peter Peruzzotti is associated with Miles Laboratories, Inc., where he has been instrumental in advancing research in prostaglandin analogues. His work has not only contributed to the scientific community but has also paved the way for potential therapeutic applications.
Collaborations
Throughout his career, Peruzzotti has collaborated with esteemed colleagues such as Warren D. Woessner and William G. Biddlecom. These collaborations have enriched his research and expanded the impact of his inventions.
Conclusion
George Peter Peruzzotti's innovative work in the field of prostaglandin analogues highlights his significant contributions to medicinal chemistry. His patents reflect a commitment to advancing cardiovascular health through scientific innovation.