Location History:
- Redmond, WA (US) (1996 - 1999)
- Seattle, WA (US) (1999 - 2000)
Company Filing History:
Years Active: 1996-2000
Title: **Innovative Contributions of George J. Schreiber in Cancer Research**
Introduction
George J. Schreiber is a prominent inventor based in Seattle, WA, known for his significant contributions to cancer research through innovative inventions. With a total of 4 patents to his name, his work primarily focuses on the development of novel antibodies and immunotoxins that target human carcinoma cells, potentially revolutionizing therapeutic approaches in oncology.
Latest Patents
Schreiber's latest inventions include methods for determining the presence of carcinoma using advanced antigen technology. His notable patents encompass the development of various antibodies, antibody fragments, and conjugates that demonstrate a high degree of selectivity for carcinoma cells. Among these inventions is the murine monoclonal antibody BR96 and its human/murine chimeric counterpart, ChiBR96. These antibodies are not only reactive with specific cell membrane antigens on the surface of human carcinomas but also possess the ability to mediate important cytotoxic activities, enhancing their potential in therapeutic applications. The antibodies developed by Schreiber can internalize within the carcinoma cells, making them particularly effective as components of antibody-drug or antibody-toxin conjugates. Notably, they display cytotoxic properties even in their unmodified form at specified concentrations, showcasing their therapeutic promise.
Career Highlights
Throughout his career, George J. Schreiber has held important positions at notable companies such as Bristol-Myers Squibb Company and Oncogen Limited Partnership. His work in these organizations has significantly advanced the field of cancer research, contributing to the understanding and treatment of carcinoma.
Collaborations
In his innovative journey, Schreiber has collaborated with esteemed colleagues, including Karl E. Hellstrom and Kim Folger Bruce. Their collective expertise has enriched the research and development process, leading to groundbreaking inventions in cancer therapeutics.
Conclusion
George J. Schreiber’s work exemplifies the critical intersection of science and innovation, particularly in the fight against cancer. His pioneering inventions and research endeavors have the potential to enhance cancer therapies, ultimately benefiting countless patients. Through his significant contributions, Schreiber continues to inspire future generations of inventors and researchers in the field of medical science.