George J Fennington, Jr

Title: Innovations by George J Fennington, Jr.

Introduction

George J Fennington, Jr. is an accomplished inventor based in Huntington Station, NY (US). He holds 2 patents that showcase his contributions to the field of biotechnology and medical devices. His innovative approaches have led to significant advancements in the purification and measurement of biological materials.

Latest Patents

Fennington's latest patents include the IRX-2 modified manufacturing process. This highly efficient method involves purifying mononuclear cells (MNCs) using an automated cell processor. The process effectively removes contaminating cells by loading leukocytes onto lymphocyte separation medium (LSM) and centrifuging the medium to obtain purified MNCs. The MNCs are then stored overnight in a closed sterile bag system. The induction mixture of the MNCs is stimulated with phytohemagglutinin (PHA) or other mitogens and ciprofloxacin in a scalable cell culture device. The resulting primary cell derived biologic is produced by filtering out the mitogen, incubating the mixture, and clarifying it through filtration. The final product is cleared from adventitious agents using anion exchange chromatography and filtration, ensuring a contamination-free primary cell derived biologic.

Another notable patent is the Gauge Tee device. This invention is a disposable sanitary gauge tee designed for pressure measurement of fluid in disposable tubing. It features a body with a main fluid passageway that connects to a pressure fluid passageway. The design includes a hose barb for removable attachment of disposable tubing and a distal end for attaching a sanitary pressure gauge. The gauge tee achieves a no dead zone configuration, allowing for total fluid transfer during measurement.

Career Highlights

Throughout his career, Fennington has worked with various companies, including Irx Therapeutics, Inc. His innovative work has contributed to advancements in medical technology and biotechnology.

Collaborations

Fennington has collaborated with notable individuals, including Harvey Brandwein and Harvey J Brandwein. These collaborations have further enhanced his contributions to the field.

Conclusion

George J Fennington, Jr. is a notable inventor whose work in biotechnology has led to significant advancements in the purification and measurement of biological materials. His patents reflect his commitment to innovation and excellence in the field.