Location History:
- Gaithersburg, MD (US) (1986)
- Germantown, MD (US) (1987)
Company Filing History:
2 out of 832,812 Years Active: 1986-1987
Title: George H. Yoakum: Innovator in Biotechnology
Introduction
George H. Yoakum is a notable inventor based in Gaithersburg, MD (US). He has made significant contributions to the field of biotechnology, particularly in the development of methods for DNA transfection and the production of polyethylene glycol (PEG) reagents. With a total of 2 patents, his work has had a meaningful impact on scientific research and applications.
Latest Patents
Yoakum's latest patents include a process for the production of improved polyethylene glycol (PEG) and a modified protoplast fusion method for high-frequency DNA transfection in human cells. The PEG reagent patent addresses the toxicity issues associated with known PEG-fusion reagents by incorporating a purification method that effectively removes toxic elements. This innovation enhances the safety and efficacy of PEG preparations. The protoplast fusion method patent describes a technique that allows for stable transfection of human cells with plasmids at frequencies greater than 10^-3. This method enables researchers to test the biological effects of individual genes, including oncogenes and viral genes, thereby advancing the understanding of gene function and expression.
Career Highlights
Throughout his career, George H. Yoakum has focused on developing innovative solutions in biotechnology. His work has contributed to advancements in genetic research and therapeutic applications. His patents reflect a commitment to improving existing methods and creating new opportunities for scientific exploration.
Collaborations
Yoakum has collaborated with notable colleagues in his field, including Curtis C. Harris and Brent E. Korba. These partnerships have fostered a collaborative environment that enhances the quality and impact of their research.
Conclusion
George H. Yoakum's contributions to biotechnology through his patents and collaborative efforts highlight his role as an influential inventor. His work continues to inspire advancements in genetic research and therapeutic applications.