Company Filing History:
1 out of 4,179 
1 out of 832,812 Years Active: 1996-2003
Title: George H Shimer, Jr: Innovator in Antifungal Research
Introduction
George H Shimer, Jr. is a notable inventor based in Boston, MA (US). He has made significant contributions to the field of antifungal research, holding 2 patents that focus on innovative methods for identifying antifungal targets and improving amplification techniques.
Latest Patents
One of his latest patents is titled "Method to identify fungal genes useful as antifungal targets." This invention provides methods for identifying nucleic acids and polypeptides derived from fungi that are useful as antifungal targets for diagnosis and/or treatment of fungal diseases. The invention also includes isolated fungal-specific nucleic acids and polypeptides comprising antifungal targets. Additionally, it offers methods for identifying antifungal agents that interact with and/or alter the function of these antifungal targets.
Another significant patent is "Ligase chain reaction with endonuclease IV correction and contamination." This invention involves methods of improving the Ligase Chain Reaction (LCR) amplification schemes by modifying at least one probe end to reduce the probability of spurious ligation and signal development. The modified ends are corrected by endonuclease IV in a target-dependent fashion, allowing participation of the probe in the enzymatic ligation reaction. Specific modifications include 3' phosphate blocking groups and nucleic acid overhangs containing an abasic site at the point of ligation.
Career Highlights
Throughout his career, George H Shimer, Jr. has worked with prominent organizations, including Abbott Laboratories Corporation. His work has significantly advanced the understanding and treatment of fungal diseases.
Collaborations
He has collaborated with notable individuals in his field, including Keith C Backman and John J Carrino. These collaborations have contributed to the development of his innovative patents and research.
Conclusion
George H Shimer, Jr. is a distinguished inventor whose work in antifungal research has led to valuable patents that enhance the diagnosis and treatment of fungal diseases. His contributions continue to impact the field significantly.