Georg Nesch

Title: Georg Nesch: Innovator in Enzymatic Solutions

Introduction

Georg Nesch is a notable inventor based in Munich, Germany. He has made significant contributions to the field of enzymatic solutions, particularly in the labelling of nucleic acids. With a total of 2 patents, his work has had a considerable impact on molecular biology.

Latest Patents

Nesch's latest patents include "Stabilized liquid mixtures for labelling nucleic acids" and "Restriction endonuclease cleaving palindromic DNA." The first patent provides stable enzyme compositions in liquid form for both radioactive and non-radioactive labelling of nucleic acids and oligonucleotides. These mixtures, which contain 30-60% (v/v) glycerin, maintain their activity when stored between -20 °C and +4 °C for at least 12 months. The second patent introduces restriction endonuclease Asp 718, which cleaves DNA at specific palindromic recognition sequences. This endonuclease, derived from Achromobacter species 718, DSM 2969, is instrumental in obtaining DNA fragments for nucleotide sequencing and various DNA analyses.

Career Highlights

Georg Nesch is currently associated with Boehringer Mannheim GmbH, where he continues to innovate in the field of enzymatic solutions. His work has been pivotal in advancing techniques used in molecular biology laboratories.

Collaborations

Nesch has collaborated with notable colleagues, including Irmgard Obermaier and Michael J Comer. Their combined expertise has contributed to the successful development of innovative solutions in their field.

Conclusion

Georg Nesch's contributions to enzymatic solutions and molecular biology are noteworthy. His patents reflect a commitment to advancing scientific research and practical applications in the labelling of nucleic acids.