Company Filing History:
Years Active: 2000-2007
Title: Innovations of Gavin D Meredith
Introduction
Gavin D Meredith is an accomplished inventor based in Cardiff-by-the-Sea, CA (US). He has made significant contributions to the field of enzymatic activity detection, holding a total of 3 patents. His work focuses on innovative methods that enhance the understanding of intracellular chemical reactions.
Latest Patents
One of his latest patents is titled "Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility." This invention measures the activity of intracellular chemical reactions by utilizing fluorescently labeled substrate molecules. These molecules undergo a change in electrophoretic mobility when they react chemically, typically catalyzed by specific enzymes. The method ensures specificity by employing labeled substrate molecules that are only acted upon by designated enzymes. Measurements are taken at a critical time, usually after the cell has been exposed to a stimulus that activates a particular enzymatic pathway. To maintain accuracy, it is essential to conduct measurements promptly to minimize subsequent chemical reactions. The process involves fast controllable laser lysis to extract the contents of a single cell, which are then analyzed through capillary electrophoresis. The enzymatic activity is determined by comparing the amounts of substrate molecules to those that have been enzymatically altered, identified by their fluorescent labels.
Career Highlights
Gavin D Meredith has established a notable career at the University of California, where he continues to innovate and contribute to scientific research. His work has implications for various fields, including biochemistry and molecular biology.
Collaborations
He has collaborated with esteemed colleagues such as Nancy L Allbritton and Christopher E Sims, further enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Gavin D Meredith's innovative approaches to detecting enzymatic activity represent a significant advancement in the field. His contributions not only further scientific understanding but also pave the way for future research and applications.