Gary W Cleary

Title: Gary W Cleary: Innovator in Transdermal Therapeutics

Introduction

Gary W Cleary is a notable inventor based in Palo Alto, California. He has made significant contributions to the field of transdermal drug delivery systems. His innovative approach has led to the development of a therapeutic system that enhances the administration of clonidine.

Latest Patents

Gary W Cleary holds a patent for a therapeutic system for administering clonidine transdermally. This system is designed in the form of a skin patch that delivers an initial priming dose of clonidine, ranging from 10 to 300 mcg/cm² of skin. This initial dose elevates the concentration of clonidine in the bloodstream to a level that stimulates alpha-adrenergic receptors without causing intolerable side effects. Following this, the system provides a continuous dosage of clonidine, maintained at a rate of 0.1 to 100 mcg/hr. The patch consists of a four-layer laminate, which includes a protective backing, a gelled reservoir for clonidine, a microporous membrane to control dosage, and a contact adhesive layer that secures the patch to the skin.

Career Highlights

Throughout his career, Gary has worked with prominent companies in the pharmaceutical industry. He has been associated with Alza Corporation and Boehringer Ingelheim GmbH, where he contributed to the advancement of drug delivery technologies. His work has been instrumental in developing innovative solutions for therapeutic applications.

Collaborations

Gary has collaborated with notable professionals in his field, including Santosh K Chandrasekaran and Siegfried Darda. These collaborations have further enriched his contributions to transdermal therapeutics.

Conclusion

Gary W Cleary's innovative work in transdermal drug delivery systems exemplifies the impact of inventors in the medical field. His patent for a clonidine skin patch represents a significant advancement in therapeutic administration methods.