Virginia Beach, VA, United States of America

Gary L Pittenger



Average Co-Inventor Count = 4.6

ph-index = 5

Forward Citations = 80(Granted Patents)


Location History:

  • Virgina Beach, VA (US) (1998)
  • Virginia Beach, VA (US) (1998 - 2006)

Company Filing History:


Years Active: 1998-2006

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6 patents (USPTO):Explore Patents

Title: Innovations and Contributions of Gary L Pittenger

Introduction

Gary L Pittenger is a notable inventor based in Virginia Beach, VA, with a significant contribution to the field of biotechnology. He holds a total of six patents, showcasing his innovative approach to scientific challenges. His work primarily focuses on the expression and functionality of proteins involved in pancreatic islet neogenesis.

Latest Patents

One of his latest patents addresses the high level of expression of INGAP in bacterial and eukaryotic cells. This patent highlights the removal of the nucleotide sequence encoding the signal peptide from the INGAP coding sequence, which allows cultured cells to express substantial amounts of INGAP activity. Previous attempts had yielded only low amounts of INGAP, likely due to the toxic nature of the signal sequence to the cells. Another significant patent involves the INGAP protein's role in pancreatic islet neogenesis. This research indicates that cellophane wrapping of hamster pancreas induces the proliferation of duct epithelial cells, followed by endocrine cell differentiation and islet neogenesis. Through the mRNA differential display technique, a cDNA clone expressed in cellophane-wrapped pancreata was identified, leading to the discovery of a previously uncharacterized gene named INGAP.

Career Highlights

Gary has worked with esteemed institutions such as Eastern Virginia Medical School of the Medical College of Hampton Roads and McGill University. His career reflects a commitment to advancing medical science through innovative research and development.

Collaborations

Throughout his career, Gary has collaborated with notable professionals, including Aaron I Vinik and Lawrence Rosenberg. These collaborations have contributed to the depth and impact of his research.

Conclusion

Gary L Pittenger's contributions to biotechnology and his innovative patents demonstrate his dedication to advancing medical science. His work continues to influence the field and inspire future research endeavors.

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