Location History:
- Thornton, PA (US) (2018)
- Thorton, PA (US) (2024)
Company Filing History:
Years Active: 2018-2024
Title: Gary Koretzky: Innovator in Immunotherapy
Introduction
Gary Koretzky is a prominent inventor based in Thornton, PA (US). He has made significant contributions to the field of immunotherapy, particularly in enhancing the efficacy of T cell therapies. With a total of 2 patents, his work focuses on innovative methods to improve cancer treatment and immune response.
Latest Patents
Koretzky's latest patents revolve around the inhibition of diacylglycerol kinase (DGK) to augment adoptive T cell transfer. The inventions provide compositions and methods for inhibiting one or more DGK isoforms in a cell to enhance its cytolytic activity. In particular, these cells can be modified to express a chimeric antigen receptor (CAR). By inhibiting DGK in T cells used in adoptive transfer, the cytolytic activity of these T cells is increased, which may be beneficial in treating various conditions, including cancer, infections, and immune disorders.
Career Highlights
Gary Koretzky is affiliated with the University of Pennsylvania, where he continues to advance research in immunotherapy. His work has been instrumental in developing new therapeutic strategies that leverage the body's immune system to fight diseases.
Collaborations
Koretzky has collaborated with notable colleagues such as Steven M. Albelda and Liang-Chuan Wang, contributing to a rich environment of innovation and research.
Conclusion
Gary Koretzky's contributions to immunotherapy through his patents and research at the University of Pennsylvania highlight his role as a key innovator in the field. His work continues to pave the way for advancements in cancer treatment and immune system enhancement.