Company Filing History:
Years Active: 2005
Title: Gary A DeCrezcenzo: Innovator in Metalloprotease Inhibition
Introduction
Gary A DeCrezcenzo is a notable inventor based in St. Charles, MO (US). He has made significant contributions to the field of medicinal chemistry, particularly in the development of metalloprotease inhibitors. His work focuses on addressing conditions associated with pathological matrix metalloprotease activity.
Latest Patents
Gary A DeCrezcenzo holds a patent for an "Aromatic sulfone hydroxamic acid metalloprotease inhibitor." This patent discloses a treatment process that involves administering an effective amount of an aromatic sulfone hydroxamic acid. This compound exhibits excellent inhibitory activity against matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13, while showing substantially less inhibition of MMP-1. The invention aims to provide therapeutic benefits for patients suffering from conditions linked to excessive MMP activity.
Career Highlights
Throughout his career, Gary has been associated with Pharmacia Corporation, where he has contributed to various research initiatives. His innovative approach to drug development has led to advancements in the treatment of diseases related to metalloprotease activity. His patent reflects his commitment to improving patient outcomes through targeted therapies.
Collaborations
Gary has collaborated with esteemed colleagues, including Thomas E Barta and Daniel Paul Becker. These partnerships have fostered a collaborative environment that enhances the research and development process.
Conclusion
Gary A DeCrezcenzo's work in the field of metalloprotease inhibition exemplifies the impact of innovative thinking in medicine. His contributions continue to pave the way for new therapeutic strategies that address critical health challenges.