This inventor holds 3 USPTO granted patents, plus 1 CIPO patent and 1 EPO patent. Top assignee: G.d. Searle & Company. Active years: 2000-2003.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2000-2003
Title: Gary A De Crescenzo: Innovator in Medicinal Chemistry
Introduction
Gary A De Crescenzo is a notable inventor based in St. Charles, MO (US). He has made significant contributions to the field of medicinal chemistry, particularly in the development of compounds that inhibit metalloprotease enzymes and retroviral proteases. With a total of 3 patents to his name, De Crescenzo's work has the potential to impact therapeutic approaches for various medical conditions.
Latest Patents
One of his latest patents is focused on an aromatic sulfone hydroxamic acid metalloprotease inhibitor. This treatment process involves administering an effective amount of a compound that exhibits excellent inhibitory activity against matrix metalloprotease (MMP) enzymes, such as MMP-2, MMP-9, and MMP-13. The invention aims to provide a therapeutic option for conditions associated with pathological matrix metalloprotease activity while minimizing inhibition of MMP-1. The compounds disclosed correspond to a specific structural formula, allowing for selective activity in therapeutic applications.
Another significant patent involves heterocyclecarbonyl amino acid hydroxyethylamino sulfonamide compounds, which serve as effective retroviral protease inhibitors, particularly against HIV protease. This invention outlines methods for inhibiting retroviral proteases, which can be crucial in preventing retroviral infections and treating existing infections.
Career Highlights
Throughout his career, Gary A De Crescenzo has worked with prominent companies in the pharmaceutical industry, including G.D. Searle & Company and Pfizer Products Inc. His experience in these organizations has contributed to his expertise in drug development and innovation in medicinal chemistry.
Collaborations
De Crescenzo has collaborated with notable professionals in his field, including Joseph J McDonald and Daniel P Getman. These collaborations have likely enhanced his research and development efforts, leading to impactful innovations.
Conclusion
Gary A De Crescenzo's contributions to medicinal chemistry through his patents and collaborations highlight his role as an innovator in the field. His work continues to pave the way for advancements in therapeutic treatments.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile