Garry Musso

Title: Garry Musso: Innovator in Long-Acting Parathyroid Hormone

Introduction

Garry Musso is a notable inventor based in Harwich, MA (US). He has made significant contributions to the field of biochemistry, particularly in the development of long-acting parathyroid hormone peptides. His innovative work has the potential to greatly impact medical treatments related to calcium regulation in the body.

Latest Patents

Garry Musso holds a patent for a long-acting parathyroid hormone peptide (PTH). This invention provides a peptide that remains in a subject's blood serum for extended periods, far exceeding the natural hormone's duration. The long-acting PTH is conjugated at the carbon 3 position of a non-hormonal vitamin D, utilizing a scaffold of discreet length that enhances purification, detection, solubility, and efficacy at the PTH receptor (PTHR). The PTH may be conjugated to the non-hormonal vitamin D through a 36 mer poly(ethylene glycol) moiety, referred to as PTH-PEG36-VitD. This innovative formulation boasts a significantly improved serum half-life and bioavailability compared to non-conjugated PTH peptides. Additionally, PTH-PEG36-VitD effectively increases serum calcium levels, reduces urinary calcium, and lowers serum phosphate.

Career Highlights

Garry Musso is associated with Extend Biosciences, Inc., where he continues to advance his research and development efforts. His work in the field of parathyroid hormone peptides showcases his commitment to improving therapeutic options for patients.

Collaborations

Garry collaborates with talented individuals such as Tarik Soliman and Daniel B Hall, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Garry Musso's contributions to the field of biochemistry, particularly through his patent for long-acting parathyroid hormone, highlight his role as an influential inventor. His work promises to enhance medical treatments and improve patient outcomes in calcium regulation.