Garfield P Royer

Title: Innovations of Garfield P Royer

Introduction

Garfield P Royer is a notable inventor based in Elburn, IL (US). He has made significant contributions to the field of biotechnology, particularly in the development of methods and compositions for ligating ligands. With a total of 5 patents to his name, Royer's work has advanced the understanding and application of polynucleotide probes.

Latest Patents

One of his latest patents is titled "Template-directed photoligation." This patent presents methods, apparatus, and compositions for ligating ligands that bind to a common receptor. An embodiment of this invention includes polynucleotide probes with photoreactive functional groups. These probes can assume substantially contiguous reactive positions on a target polynucleotide, placing the photoreactive group in juxtaposition. When activated by radiant energy, the photoreactive functional groups form a probe reaction product, binding the probes together.

Another significant patent is the "Template-directed ligation and amplification assay." This method is designed for detecting a target polynucleotide sequence, using the target sequence as a template to direct the hybridization of first and second polynucleotide probes. The hybridized probes are then ligated, preferably through covalent linkage of photoreactive functional groups present on each probe, resulting in a ligated reaction product. This product is subsequently multiplied with a polymerase, such as Q-beta replicase, to produce an enzyme reaction product that can be detected. The presence of this enzyme reaction product indicates the presence of the target polynucleotide sequence.

Career Highlights

Garfield P Royer has worked with prominent companies in the biotechnology sector, including Amoco Corporation and Vysis, Inc. His experience in these organizations has contributed to his expertise and innovative capabilities in the field.

Collaborations

Throughout his career, Royer has collaborated with notable individuals such as Larry E Morrison and Kenneth A Cruickshank. These collaborations have likely enriched his work and led to further advancements in his inventions.

Conclusion

Garfield P Royer is a distinguished inventor whose contributions to biotechnology have been significant. His innovative patents and collaborations reflect his dedication to advancing the field. His work continues to influence the development of new technologies in the realm of polynucleotide research.