Gang Qin

Title: Gang Qin: Innovator in Antibody-Drug Conjugation Technologies

Introduction

Gang Qin is a prominent inventor based in Suzhou, China, known for his significant contributions to the field of biotechnology. With a total of 14 patents to his name, he has made remarkable advancements in the development of conjugation devices and methods for producing conjugates. His work has the potential to revolutionize the way antibody-drug conjugates are created, enhancing therapeutic options in medicine.

Latest Patents

Among his latest patents, Gang Qin has developed a conjugation device and method for producing conjugates. This innovative device includes a flow reactor filled with a support matrix, which contains chromatography beads, fibers, or membranes, along with an immobilized biologic catalyzer, specifically the enzyme ligase. The device is designed to continuously provide reaction fluids, facilitating a conjugation reaction between the first and second moieties of a conjugate under the catalysis of ligase.

Another notable patent involves an immobilized endoglycosidase fusion protein and its use in preparing antibody-drug conjugates. This method allows for site-directed conjugation based on an N-glycosylation site of an antibody's Fc region. The process includes covalently linking an activated donor containing an oxazoline oligosaccharide to an antibody, achieving one-step conjugation through the catalytic action of the endoglycosidase.

Career Highlights

Gang Qin has worked with several companies, including Genequantum Healthcare (Suzhou) Co., Ltd. and Lisure Science (Suzhou) Co., Ltd. His experience in these organizations has contributed to his expertise in the field of biotechnology and innovation.

Collaborations

Some of his notable coworkers include Cao Lv and Joachim Walter, who have collaborated with him on various projects related to his patents and innovations.

Conclusion

Gang Qin's work in the field of antibody-drug conjugation technologies showcases his innovative spirit and dedication to advancing medical science. His patents reflect a commitment to improving therapeutic methods, which could have a lasting impact on healthcare.