Gandara Amarasinghe

Title: The Innovative Contributions of Gandara Amarasinghe

Introduction

Gandara Amarasinghe is a notable inventor based in Iowa City, IA (US). He has made significant contributions to the field of chemistry, particularly in the development of aziridine derivatives. With a total of 2 patents, his work has implications in diagnostic imaging and chelating agents.

Latest Patents

Amarasinghe's latest patents include the preparation of n-arylmethyl aziridine derivatives and 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom. His inventions focus on the utility of aziridines in cyclooligomerization reactions, which can produce polyazacycloalkane compounds. These compounds are particularly useful in the preparation of chelating agents for diagnostic imaging contrast agents. Notably, N-benzyl-aziridine can be cyclotetramerized and debenzylated to yield cyclen, a key intermediate in the preparation of these agents. His inventions provide an attractive route to the production of N-benzyl and other N-arylmethyl aziridines.

Career Highlights

Throughout his career, Amarasinghe has worked with reputable organizations such as Nycomed Salutar, Inc. and the University of Iowa Research Foundation. His experience in these institutions has contributed to his innovative research and development in the field of chemistry.

Collaborations

Amarasinghe has collaborated with notable colleagues, including Janis Vasilevskis and John Varadarajan. These collaborations have further enhanced his research and the impact of his inventions.

Conclusion

Gandara Amarasinghe's contributions to the field of chemistry through his innovative patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of important compounds in diagnostic imaging.