Company Filing History:
Years Active: 2009
Title: Galina Denisova: Innovator in Antigenic Epitope Research
Introduction
Galina Denisova is a prominent inventor based in Tel Aviv, Israel. She has made significant contributions to the field of immunology, particularly in the study of binding surfaces associated with monoclonal antibodies. Her innovative work has the potential to impact vaccine development for HIV.
Latest Patents
Galina Denisova holds a patent for "Mapping and reconstitution of a conformational discontinuous binding surface." This patent focuses on the structure of conformational, discontinuous binding surfaces that associate with binding molecules, specifically the epitopes of monoclonal antibodies (mAbs). The invention involves selecting specific peptides from a peptide library, which are then used to define a binding surface database. A novel computer algorithm analyzes the crystalline structure of the original binding surface, allowing for the reconstitution of antigenic epitope-mimetics recognized by their original mAbs. This research is crucial for developing vaccines aimed at preventing or treating HIV.
Career Highlights
Galina Denisova has established herself as a key figure in her field through her innovative research and patent contributions. Her work at Ramot at Tel Aviv University Ltd. has positioned her at the forefront of immunological research.
Collaborations
Some of her notable coworkers include Jonathan M Gershoni and Erez Moshe Bublil. Their collaborative efforts have further advanced the research in the area of binding surfaces and antibody recognition.
Conclusion
Galina Denisova's contributions to the field of immunology through her patent and research are noteworthy. Her work not only enhances our understanding of antibody interactions but also paves the way for future vaccine developments.