Gail T Colbern

Title: Gail T. Colbern: Innovator in Liposome Technology

Introduction

Gail T. Colbern is a prominent inventor based in Pacifica, California. She has made significant contributions to the field of pharmaceutical technology, particularly in the development of liposome-entrapped topoisomerase inhibitors. With a total of 6 patents to her name, Colbern's work has the potential to impact therapeutic approaches in cancer treatment.

Latest Patents

One of her latest patents focuses on a composition for the administration of a therapeutically effective dose of a topoisomerase inhibitor. This innovative composition includes liposomes that define an aqueous compartment, composed of a vesicle-forming lipid and a lipid derivatized with a hydrophilic polymer. The design allows for a coating of hydrophilic polymer chains on both the inner and outer surfaces of the liposomes. The topoisomerase inhibitor is entrapped within the liposomes at a concentration of at least about 0.10 μmole drug per μmole lipid, enhancing its therapeutic efficacy.

Career Highlights

Throughout her career, Gail T. Colbern has worked with notable organizations such as Alza Corporation and the University of California. Her experience in these institutions has allowed her to refine her expertise in drug delivery systems and liposome technology.

Collaborations

Colbern has collaborated with esteemed colleagues, including James L. Slater and Peter K. Working. These partnerships have contributed to her innovative research and development efforts in the pharmaceutical field.

Conclusion

Gail T. Colbern's contributions to liposome technology and her innovative patents highlight her role as a leading inventor in the pharmaceutical industry. Her work continues to pave the way for advancements in drug delivery systems, showcasing the importance of innovation in healthcare.