Gail L Astle

Title: Gail L. Astle: Innovator in Antibiotic Recovery

Introduction

Gail L. Astle is a notable inventor based in Princeton, NJ (US). She has made significant contributions to the field of antibiotic recovery, particularly through her innovative methods. Her work has implications for the pharmaceutical industry, especially in the production of polyether antibiotics.

Latest Patents

Gail L. Astle holds a patent for a method for isolating polyether antibiotics. This method involves recovering antibiotics such as lonomycin, monensin, or ionomycin from fermentation broth. The process begins with extracting the polyether using a water-immiscible solvent, such as ethyl acetate. The resulting extracts are then concentrated, dissolved in aqueous methanol, and extracted into hexane, benzene, or mixtures thereof. Ultimately, the polyether is recovered in crystalline form directly from the latter extract. She has 1 patent to her name.

Career Highlights

Gail L. Astle has worked at E.R. Squibb & Sons, Inc., where she has been able to apply her expertise in antibiotic recovery. Her innovative methods have contributed to advancements in the field and have been recognized within the industry.

Collaborations

Throughout her career, Gail has collaborated with notable colleagues, including Wen-Chih Liu and William E. Brown. These collaborations have further enhanced her research and development efforts in antibiotic recovery.

Conclusion

Gail L. Astle is a pioneering inventor whose work in isolating polyether antibiotics has made a significant impact on the pharmaceutical industry. Her innovative methods continue to influence antibiotic production and recovery processes.