Location History:
- Cilavegna-Pavia, IT (2001)
- Pavia, IT (2002)
Company Filing History:
Years Active: 2001-2002
Title: Gabriele Fachin: Innovator in Bioactive Derivatives
Introduction
Gabriele Fachin is a notable inventor based in Pavia, Italy. He has made significant contributions to the field of pharmaceuticals, particularly in the development of bioactive derivatives of camptothecin. With a total of two patents to his name, his work focuses on enhancing the efficacy and safety of cancer treatments.
Latest Patents
Fachin's latest patents include innovative formulations that improve the therapeutic profile of camptothecin. One of his patents describes water-soluble polymeric conjugates of camptothecin, which consist of N-(2-hydroxypropyl)methacryloylamide units linked to camptothecin residues such as irinotecan. These conjugates demonstrate enhanced antitumor activity while reducing toxicity compared to the free drug. Another patent involves polymeric derivatives of camptothecins, specifically 20-O-[glycyl-aminoacyl-glycyl]-camptothecins, along with a process for their production.
Career Highlights
Fachin is currently associated with Pharmacia & Upjohn S.p.a., where he continues to advance his research in pharmaceutical innovations. His work has been pivotal in developing new therapeutic strategies for cancer treatment.
Collaborations
Fachin collaborates with esteemed colleagues such as Francesco Angelucci and Valeria Caiolfa, contributing to a dynamic research environment that fosters innovation.
Conclusion
Gabriele Fachin's contributions to the field of pharmaceuticals, particularly through his patents on camptothecin derivatives, highlight his role as a significant innovator in cancer treatment. His work continues to pave the way for advancements in therapeutic options for patients.