Company Filing History:
5 out of 21 
4 out of 4 
1 out of 2 Years Active: 2010-2016
Title: Innovations in Cancer Treatment by Inventor Gabriela Rossi
Introduction
Gabriela Rossi is a prominent inventor based in Ankeny, Iowa, known for her significant contributions to cancer treatment through innovative methods and compositions. With a total of 10 patents to her name, she has made remarkable strides in enhancing the immunogenicity of tumor-associated antigens.
Latest Patents
One of her latest patents focuses on the "Enhanced immunogenicity of tumor associated antigens by addition of alpha-gal epitopes." This invention relates to methods and compositions designed to selectively target and kill tumor cells. It describes prophylactic or therapeutic cancer vaccines based on purified tumor-associated antigen (TAA) proteins or TAA-derived synthetic peptides. These peptides are altered through various methods to introduce αGal epitopes, which enhance the opsonization of the antigen by natural anti-αGal antibodies. This process stimulates the immune system to produce tumor-specific cytotoxic cells and antibodies that attack and eliminate tumor cells.
Another significant patent is "Antitumor vaccination using allogeneic tumor cells expressing alpha (1,3)-galactosyltransferase." This invention also aims to selectively target and kill tumor cells. It involves ex vivo gene therapy protocols where tumor cells are engineered to express an α(1,3)galactosyl epitope. After irradiation or other methods to kill the cells, they are administered to a patient. The α-galactosyl epitope enhances the uptake of the opsonized tumor cell by antigen-presenting cells, resulting in improved tumor-specific antigen presentation and stimulating the immune system to produce tumor-specific cytotoxic cells and antibodies.
Career Highlights
Gabriela Rossi has worked with notable organizations such as Newlink Genetics Corporation and Central Iowa Health System. Her work in these companies has contributed to the advancement of cancer therapies and has positioned her as a leader in her field.
Collaborations
Some of her notable coworkers include Charles J. Link and Tatiana Seregina, who have collaborated with her on various projects aimed at improving cancer treatment methodologies.
Conclusion
Gabriela Rossi's innovative work in cancer treatment through her patents demonstrates her commitment to advancing medical science. Her contributions have the potential to significantly impact the field of oncology and improve patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.