Title: Gabriel-Marcus Butilca: Innovator in Bivalirudin Production
Introduction: Gabriel-Marcus Butilca is an inventor based in Karmiel, Israel. He is currently associated with Novetide Ltd., where he focuses on innovative methods in biopharmaceutical production. Although he has not yet been granted any patents, his work is significant in the field of high-purity polypeptides.
Latest Patent Applications: Gabriel-Marcus Butilca's latest patent application is titled "Process for Production of Bivalirudin." This invention relates to methods for the preparation of high purity Bivalirudin. The polypeptide is prepared in a high purity of at least 98.5% (by HPLC), wherein the total impurities amount to less than 1.5%. This includes not more than 0.5% [Asp-Bivalirudin] and each impurity being less than 1.0%. Preferably, the purity is at least about 99.0% by HPLC, with total impurities amounting to less than 1.0%, comprising not more than 0.5% [Asp-Bivalirudin] and each impurity being less than 0.5%.
Conclusion: Gabriel-Marcus Butilca is making strides in the field of biopharmaceuticals, particularly in the production of Bivalirudin. His innovative approaches may lead to significant advancements in the industry.